Friday 17th - the view from my window

I have been thinking quite a bit about next generation sequencing versus microarrays. I am involved in a collaboration with a colleague at Harvard. The goal is to identify changes that occur when cells become 'immortal'. We planned to look for changes in the transcriptome using Agilent arrays. But why not also survey the genome for mutations? Next generation sequencing allows both in a single experiment because you get abundance (transcript level) and sequence information. So in the spirit of competition my last slide is to ask students and instructors at all the sites for their views on the relative power and merits of arrays and next generation sequencing for a given application.

Meanwhile here in Columbus it is sunny and beautiful. This is the view from my window. So you will see both kinds of 'football' represented in the video - the 100,000-seat stadium for watching the game with the oddly-shaped ball and some guys running around after a little round ball.